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Rhogam injection uses in urdu

RhoGAM Uses, Side Effects & Warnings - Drugs

RhoGAM is used to prevent an immune response to Rh positive blood in people with an Rh negative blood type. This medicine may also be used in the treatment of immune thrombocytopenic purpura (ITP). RhoGAM may also be used for purposes not listed in this medication guide For Intravenous or Intramuscular Injection Preservative-free, Latex-free, Ready-to-use Prefilled Syringe 1 INDICATIONS AND USAGE 1.1 Suppression of Rh Isoimmunization Pregnancy and Obstetric. RhoGAM is one brand of Rh immunoglobulin (RhIg). RhIg is an injectable drug given to pregnant people with Rh-negative blood during pregnancy. Every person is born with a blood type —O, A, B, or AB and a Rhesus (Rh) factor, which is positive or negative. A simple blood test can determine your blood type and Rh status The story of Rho(D) immunoglobulin (RhoGAM) begins in 1909 with Theobald Smith, Fabyan Professor of Comparative Pathology at Harvard, and ends in the 1960s with completion of the clinical trials. Important in the development of RhoGAM were the search for a safe diphtheria vaccine, an interest in but

Rhophylac Rh (D) Immune Globulin Intravenous (Human)

  1. RhoGAM belongs to a group of drugs called immunoglobulins. These work by making the immune system work better. This medication is available in an injectable form to be given directly into a muscle (IM) by a healthcare professional. Common side effects of RhoGAM include pain and redness at the site of injection, rash, body aches, and fevers
  2. an injection (shot) of a medicine called Rho(D) immune globulin [GLOB-yuh-lin]. This medicine is often referred to by one of its brand names, RhoGAM. Having an injection at the right time during or after pregnancy can lower your baby's risk of having a hemolytic disease. It is best to have a RhoGAM injection during pregnancy before your body ha
  3. The good news is that Rh incompatibility is easy to treat with a RhoGAM shot. What is RhoGAM? RhoGAM is the injection used to treat Rh incompatibility during pregnancy. The shot contains antibodies (collected from plasma donors) that stop your immune system from reacting to your baby's Rh positive blood cells
Blinded by the Light: A Critical Look at Rhogam and Rhesus

RhoGAM: Importance, Timing, Safety, Side Effect

  1. e whether literature supports the use of Rh immune globulin in Rh-negative women with first trimester spontaneous abortions to prevent maternal sensitization to the fetal Rh antigen and subsequent fetal morbidity and mortality. Methods: We searched MEDLINE (1966-2005), the Cochrane Central Register of Controlled Trials, EMBASE (1990 to 2005), and the reference sections of.
  2. ister RhoGAM every 12 weeks starting from first injection to maintain a level of passively acquired anti-D. If delivery occurs within three weeks after the last antepartum dose, the postpartum dose may be withheld, but a test for fetal-maternal hemorrhage should be performed to deter
  3. Find patient medical information for RhoGam Ultra-Filtered intramuscular on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings

Rho(D) immunoglobulin (RhoGAM): how it came into bein

RhoGAM is an injection made up of antibodies called immunoglobulin that help protect a fetus from its mother's antibodies. According to the product website, RhoGAM prevents the Rh-negative mother. For adolescents and adults, the deltoid muscle can be used for more than one intramuscular injection. Best practices for multiple injections include: Label each syringe with the name and the dosage (amount) of the vaccine, lot number, the initials of the preparer, and the exact beyond-use time, if applicable

RhoGAM® Ultra-Filtered Plus Rho (D) Immune Globulin (Human), Preservative Free 1500 IU (300 mcg) Intramuscular Injection Prefilled Syringe 5 Syringes. Each single dose prefilled syringe of RhoGAM contains 300 mcg (1500 IU This is the dose for the indications associated with pregnancy at or b Thimerosal fre Find everything you need to know about Rhogam (Rho (D) Immune Globulin), including what it is used for, warnings, reviews, side effects, and interactions. Learn more about Rhogam (Rho (D) Immune. We are open for safe in-person care. Learn more: Mayo Clinic facts about coronavirus disease 2019 (COVID-19) Our COVID-19 patient and visitor guidelines, plus trusted health information Latest on COVID-19 vaccination by site: Arizona patient vaccination updates Arizona, Florida patient vaccination updates Florida, Rochester patient vaccination updates Rochester and Mayo Clinic Health System. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problem

RhoGAM - Side Effects, Uses, Dosage, Overdose, Pregnancy

  1. g. Another dose is.
  2. Free translation service for online automatic translation of text and web pages, translating between many languages, including Spanish, French, Japanese, German.
  3. This medicine is used in RhO negative mothers who are pregnant with a RhO positive child. It is also used after a transfusion of RhO positive blood into a RhO negative person. The lowest GoodRx price for the most common version of Rhogam is around $106.70, 36% off the average retail price of $167.88. Compare human immunoglobulin gs
  4. Lack of Transmission of Human Immunodeficiency Virus Through Rho(D) Immune Globulin (Human) On September 18, 1987, the Armed Forces Medical Logistical Office issued instructions to temporarily suspend from distribution and use in military hospitals one lot (RHG 636) of RhoGAM* Rho(D) Immune Globulin (human) (Rh-IG), manufactured by Ortho Diagnostic Systems, Inc
  5. istration to selected pre-menopausal, Rho-D-negative females; and for treatment of selected Rho-D-positive.
  6. Erythroblastosis fetalis causes the mother's white blood cells to attack her baby's red blood cells as they would any other foreign invader. It occurs when the blood types of the mother and her.
  7. Rhogam 300mcg Injection is used in the treatment of Infections. View Rhogam 300mcg Injection (vial of 15 ml Injection) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg.co

Special immune globulins, called RhoGAM, are now used to prevent RH incompatibility in mothers who are Rh-negative. If the father of the infant is Rh-positive or if his blood type is not known, the mother is given an injection of RhoGAM during the second trimester Some women report soreness, swelling, itching, or bruising at the site of the injection. The shot is needed every week so there is a steady supply of 17P in the body. If you use 17P, it is very important that you get all of the shots once you start. The shots will be given until at least 37 weeks of pregnancy Rhogam (300mcg) 300mcg/1Vial - 1Vial Injection (Human Anti-D Immunoglobulin) drug information. Find its price or cost and dose. It is manufactured by J & J Chemicals & Pharmaceuticals Anti-D (rh) immunoglobulin is a prescription medication used to prevent Rh immunization, also known as Rh incompatibility. Anti-D (rh) immunoglobulin can also be used to treat immune thrombocytopenia purpura (ITP), a bleeding disorder, in adults. This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information

Rh Factor Treatment in Pregnancy (RhoGAM

Get Online Advice on Rhogam 300Mcg Injection from Wide Range of Doctors and Health Experts. Ask a Question and Learn More About Rhogam 300Mcg Injection at Lybrate.co The routine use of Rh D immune globulin is responsible for the reduced rate of red cell alloimmunization in more economically developed countries. First introduced in the 1970s, the postpartum administration of Rh D immune globulin reduced the rate of alloimmunization in at-risk pregnancies from approximately 13-16% to approximately 0.5-1.8.

What is the Rhogam Shot and What do I Need to Know About

Existing studies do not provide conclusive evidence that the use of anti-D during pregnancy benefits either mother or baby in terms of incidence of Rhesus D alloimmunisation during the pregnancy or postpartum, or the incidence of neonatal morbidity (jaundice) (low to very low quality evidence).However women receiving anti-D may be less likely to register a positive Kleihauer test in pregnancy. Pregnancy injections: usually specialty medications for injection or infusion in women. These drugs can be given for many reasons including to prevent pregnancy, pre-term labor, or autoimmune reactions. Most of these medications are given in a health care setting such as your doctor's office or hospital. Examples: Depo-Provera, Makena, RhoGAM It's difficult to say (or even think about), prior to their findings, how many lives had been lost. Nearly 30 years after the discovery, the first injectable was approved in the United States and England. As I enter my 28th week of pregnancy. I received my RhoGAM injection today. After delivery, I will be receiving another RhoGAM injection

What is a RhoGAM Shot and Why Is It Given During Pregnancy

Google's free service instantly translates words, phrases, and web pages between English and over 100 other languages Use this code for RhoGam, Rhophylac. J2792-Injection, Rho D immune globulin, intravenous, human, solvent detergent, 100 IU. IMMUNOSUPPRESSIVE DRUGS Atgam Not covered when administered in a home J7504 Lymphocyte immune globulin, antithymocyte globulin equine, parenteral, 250 mg. Use this code for Atgam. CellCept J7517 Mycophenolate mofetil, oral. injection-site location method, depth of needle insertion, and use of nonsyringe hand. Common reasons for unsuccessful IM injection included poor injection-site selection and not advancing the needle to full length. It was estimated that needles 38 mm (1.5 inches) or more would be needed for successful IM injection in 14% to 34% of patients. 2 Intramuscular injections offer some benefits over other types of delivery methods, such as oral, intravenous injections into a vein, and subcutaneous injections into fatty tissue under the skin Rh disease (also known as rhesus isoimmunization, Rh (D) disease) is a type of hemolytic disease of the fetus and newborn (HDFN). HDFN due to anti-D antibodies is the proper and currently used name for this disease as the Rh blood group system actually has more than 50 antigens and not only D-antigen

Quality ID #255: Rh Immunoglobulin (Rhogam) for Rh-Negative Pregnant Women at Risk of Fetal denominator criteria are used to identify the intended patient population. The numerator quality-data codes included in this specification are used to submit the quality actions allowed by the measure on the claim form(s). All measure There are two types of hydrops fetalis, immune and nonimmune. The type depends on the cause of the abnormal fluid. Immune hydrops fetalis is most often a complication of a severe form of Rh incompatibility, which can be prevented.This is a condition in which mother who has Rh negative blood type makes antibodies to her baby's Rh positive blood cells, and the antibodies cross the placenta Injection What it is - Hormone injection. - Prevents release of egg. How to use - Get an injection every 2 months (NET-EN) or 3 months (DMPA). - If breastfeeding, can start 6 weeks after childbirth. - Works best if you get your injections on time. If late for an injection: - DMPA: Can still get an injection up to 4 weeks late Biocobal 500 MCG Injection is a naturally occurring and pure form of Vitamin B12. It is taken to regulate certain vital bodily functions like cell multiplication, blood formation, and protein synthesis. It is used to treat Vitamin B12 deficiency in people with Pernicious Anemia. Buy Biocobal 500 MCG Injection Online. Know uses, side effects, dosage, contraindications, substitutes, benefit. SOLU-MEDROL (methylprednisolone sodium succinate for injection, USP) NOT FOR USE IN NEONATES CONTAINS BENZYL ALCOHOL . For Intravenous or Intramuscular Administration . DESCRIPTION . SOLU-MEDROL Sterile Powder is an anti-inflammatory glucocorticoid, which contain

Ucef 500Mg Injection is used for treating bacterial infections.It is administered to the patient in the form of an injection. It is used for the treatment of lower respiratory tract infections, skin and skin structure infections, bone and joint infections, intra-abdominal and urinary tract infections, sepsis and meningitis due to susceptible organism Find here Anti-D Injection, Anti D Injection manufacturers, suppliers & exporters in India. Get contact details & address of companies manufacturing and supplying Anti-D Injection, Anti D Injection across India In order to prevent the formation of these antibodies, you may get an injection of RhoGAM (Rh immunoglobulin or RhIg). This injection contains antibodies that will attach to any Rh-positive cells. This prevents you from developing your own antibodies that can cause problems in future pregnancies or transfusions

Do Rh-negative women with first trimester spontaneous

injection. If the injection usually is self-administered or isn't given as part of a doctor's service, Part B generally won't cover it, but a person's Medicare drug plan (Part D) may. cover these drugs under certain circumstances. In most cases, the yearly Part B deductible applies to these drugs. This mean Injection: 1%; 2% (hydrochloride) in vial. Injection for spinal anaesthesia: 5% (hydrochloride) in 2‐ml ampoule to be mixed with 7.5% glucose solution injection. (Store diluent separately at room temperature or in the refrigerator.) Contact manufacturer for exposure to above range temperature Contact manufacturer for exposure to above range temperature Varicella Vaccine, Live Varivax (Merck) Vaccine should be stored at -15C (+5F) or colder until reconstituted for injection Vancomycin Injection, USP For Intravenous Use Only To reduce the development of drug-resistant bacteria and maintain the effectiveness of vancomycin and other antibacterial drugs, vancomycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria There are a few strategies you can use to make your injections safe and painless, including numbing the area beforehand and selecting your injection site carefully. Make sure to palpate (carefully feel) your selected muscle before giving yourself an injection to make sure your muscle is large enough

RhoGAM Ultra-Filtered PLUS - FDA prescribing information

  1. istration of SCIT, focusing on those used to ad
  2. al fat) has been increasing rapidly over the past few years, very few studies.
  3. Vaccine Information Statements (VISs) are information sheets produced by the Centers for Disease Control and Prevention (CDC). VISs explain both the benefits and risks of a vaccine to adult vaccine recipients and the parents or legal representatives of. vaccinees who are children and adolescents. Federal law requires that VISs be handed out.
  4. Patients who have had a prior allergic-like reaction to intravenous iodinated contrast injections or intravenous gadolinium-based contrast injections shall be cared for under the following guidelines. II. POLICY PURPOSE To provide a standard of care for patients who have a history of allergic-like reaction to contrast materials
  5. istered = 1 unit is billed. Example 2: HCPCS description of drug is 50 mg. 200 mg are ad
  6. The Rh factor is a protein that can be found on the surface of red blood cells. If your blood cells have this protein, you are Rh positive. If your blood cells do not have this protein, you are Rh negative. During pregnancy, problems can occur if you are Rh negative and your fetus is Rh positive. Treatment can be given to prevent these problems
  7. By deep intramuscular injection. For Females of childbearing potential. 500 units, dose to be given at weeks 28 and 34 of pregnancy, if infant rhesus-positive, a further dose is still needed immediately or within 72 hours of delivery, subcutaneous route used for patients with bleeding disorders

Consumer information about the prescription injection rubella virus vaccine live (Meruvax II) used to prevent German measles (rubella) in individuals age 12 months or older. Side effects, drug interactions, dosing, storage, and pregnancy and breastfeeding information is provided Background. Vitamin D deficiency remains common in all age groups and affects skeletal and non-skeletal health. Fibroblast growth factor 23 is a bone-derived hormone that regulates phosphate and 1,25-dihydroxyvitamin D homeostasis as a counter regulatory factor. 1,25-Dihydroxyvitamin D stimulates fibroblast growth factor 23 synthesis in bone, while fibroblast growth factor 23 suppresses 1,25. Triamcinolone injection is given through a needle and can be injected into different areas of the body: into a muscle, into the space around a joint or tendon, or into a lesion on the skin. A healthcare provider will give you this injection. Not every brand of this medicine is used for the same conditions or injected into the same body areas RhoGAM (rhod immune globulin human) is a sterilized solution made from human blood used to prevent an immune response to Rh positive blood in people with an Rh negative blood type. RhoGAM may also be used in the treatment of immune thrombocytopenic purpura (ITP). Available at Al-Saif Pharmacy Order: 0345023038 Anti-D is made from the plasma of human blood, given by donors. The manufacture of blood products, including anti-D, is strictly controlled. All blood donors are screened for hepatitis B, hepatitis C and HIV, and plasma is only imported from countries that are free of variant CJD.The end product is also treated to kill or remove viruses, so the risk of contracting a virus through anti-D is.

If you miss a scheduled injection, you may not be fully protected against COVID-19. If you have any further questions on the use of this vaccine, ask your doctor, pharmacist or nurse. 4 Vitamin K injections have been routinely given in Australia for over 20 years, with no ill effects at the time of the injection, or later. Some babies have a slight soreness for a day or so at the injection site. Vitamin K injections remain the best preventive measure for reducing the risk of haemorrhagic disease of the newborn 6 min read. The hemlock woolly adelgid (HWA), Adelges tsugae, is a nonnative, invasive insect pest that colonizes, feeds on the sap of, and ultimately kills both eastern and Carolina hemlock trees, Tsuga canadensis and Tsuga caroliniana. HWA is native to Japan and was first discovered in Virginia in 1951 Fortum 1g Injection. This information is intended for use by health professionals. 1. Name of the medicinal product. Fortum 1 g powder for solution for injection or infusion. 2. Qualitative and quantitative composition. Each vial contains 1 g ceftazidime (as pentahydrate) with sodium carbonate (118 mg per gram of ceftazidime)

Bamboo Growth. Bamboo forms groves in which all of the culms (stems) are clones of the original plant. The culms emerge from a dense rhizome system, which usually is located within the upper 12 inches of soil. Rhizomes are modified underground stems that function similarly to roots SPECIAL BULLETIN COVID-19 #161: Billing for Administration of Monoclonal Antibodies. (EUA) to permit the emergency use of the unapproved products, bamlanivimab and etesevimab, to be administered together for the treatment of mild to moderate coronavirus disease 2019 (COVID-19) in adults and pediatric patients (12 years of age and older weighing. RhoGAM [ro´gam] trademark for a preparation of Rh0 (D antigen) immune globulin. The gamma globulin is derived from the plasma of women previously immunized to the Rh0 (D) antigen and is administered after each Rh-incompatible pregnancy. The gamma globulin prevents the formation of antibodies after delivery or abortion. See also rh factor. Miller-Keane.

RhoGam Ultra-Filtered Intramuscular: Uses, Side Effects

Effective with date of service May 17, 2021, the Medicaid and NC Health Choice programs cover dostarlimab-gxly injection, for intravenous use (Jemperli) for use in the Physician Administered Drug Program (PADP) when billed with HCPCS code J9999 - Not otherwise classified, antineoplastic drugs. Jemperli is available as a 500 mg/10 mL (50 mg/mL. Rhogam UF 300mcg Injection is used in the treatment of Infections. View Rhogam UF 300mcg Injection (vial of 1 ml Injection) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg.co and is prepared in a sterile concentrated solution for intramuscular injection. 2. The trade name of the globulin may change from time to time depending on the pharmaceutical provider. The globulin is commonly referred to as Rh immunoglobulin or Rhogam. II. CLINICAL FEATURES: A. Subjective Information 1. Inquire about: a • The primary codes 64479, 64483, 64490 and 64493 are used for a single injection in the cervical/thoracic or lumbar/sacral areas of the spine, respectively. Each primary code has an associated add -on code, 64480, 64491, 64492 (cervical/thoracic) and 64484, 64494 and 6449 Norman Location 250 12th Ave. N.E. Norman, OK 73071 Phone (405) 321.4048 Get Direction

RhoGAM Shot for Rh Incompatibility: Why You May Need I

Knee joint aspiration and injection are performed to aid in diagnosis and treatment of knee joint diseases. The knee joint is the most common and the easiest joint for the physician to aspirate To ensure rational and safe use of injections globally, better injection safety practices are needed. The responsibility for ensuring injection safety rests with national governments, prescribers, administrators, receivers of injections and the wider community. The World Healt Decapeptyl SR 11.25 mg has three different uses. It is used in men, women and children to treat completely different conditions. Decapeptyl SR is available in two other strengths: Decapeptyl SR 3 mg is used once a month and Decapeptyl SR 22.5 mg is used once every 6 months. Not all dose strengths are approved for all indications

RhoGAM at 50: A Columbia Drug Still Saving Lives of

Alburel (Reliance) Injection Human Normal Immunoglobulin IP, For IV use, Reliance Life Sciences. ₹ 250/ Box Get Latest Price. Composition: Albumin. Manufacturer: Reliance Life Sciences. Type: Injection. Brand: Alburel (Reliance) Usage/Application: For IV use. Packaging Size: 100 ml. read more.. Betamethasone is an inflammation-reducing corticosteroid that helps treat a range of skin conditions. Learn about the types, uses, and side effects of this medication here, as well as the warnings. Rhesus D negative in pregnancy. Rhesus disease occurs during pregnancy when there is an incompatibility between the blood types of the mother and baby. Everybody has one of 4 blood types (A, B, AB or O). You inherit your blood group from a mix of your parents' genes. These blood types are further identified as being either positive or negative The commonly used injections we use are Prostap and Zoladex. Both of these injections are GnRH analogues and drugs are only available in injection form. Prostap is administered via the intramuscular or subcutaneous route. Due to drug volume we generally give the injection in the buttock as this tends to be the largest muscle

Common and Rare Side Effects for RhoGam intramuscula

Recognizing outstanding vaccination efforts in healthcare settings. This website is supported in part by a cooperative agreement from the National Center for Immunization and Respiratory Diseases (Grant No. 6NH23IP22550) at the Centers for Disease Control and Prevention (CDC) in Atlanta, GA. The website content is the sole responsibility of IAC. NHS indicative price. Drug tariff. Drug tariff price. Anti-D (RHO) immunoglobulin 750 unit per 1 ml. 1. pre-filled disposable injection ( POM ) £76.50. — Women undergoing infertility treatment are all too familiar with the need to administer injections, whether subcutaneous (beneath the skin) or intramuscular. Although the commonly used fertility drug clomiphene is taken in pill form, a great many of the drugs required for women being treated for infertility necessitate getting a shot- typically, many shots - over a period of days to weeks

Rho(D) immune globulin - Wikipedi

A recent study looks at the effects of the SARS-CoV-2 spike proteins, showing that they can cause some of the harm of COVID-19 by themselves. This is an important advance in our understanding of the disease and hopefully will lead to new therapeutic interventions. The spike protein is what gives the coronavirus family of viruses their name Rhesus disease can largely be prevented by having an injection of a medication called anti-D immunoglobulin. This can help to avoid a process known as sensitisation, which is when a woman with RhD negative blood is exposed to RhD positive blood and develops an immune response to it I am Rh- as was my husband, so no Rhogam was needed. My children were born in 1979, 1984 and 1992. The rhogam shot was discussed, but of course it was not needed. But I want to point out that at that point the Rhogam shot was only given AFTER birth - not during pregnancy. But now the Rhogam shot is given routinely at 28 weeks gestation Vaccinations & injections. Whether it's a flu shot or a vaccination for pneumonia, whooping cough or meningitis, we can help. We offer vaccines for children, adolescents, teens and adults, and certain injections for adults. It's easy to bring your family and get them covered, all on your schedule. Please see the vaccination or injection page.

Separating Fact from Fiction in Maternal-Fetal Medicine

Treatment with medicine By Adil Onset injection Onset 2mg Injection is an antiemetic medicine commonly used to control nausea a.. The most common side effects with the injection are bone, muscle and joint pains, flu like illness and headache. The flu like symptoms generally disappears after 24-48 hours and usually occurs only after the first injection. The most common side effects with the pill are diarrhea, pain in the extremities, and upset stomach Hevert ® Calmvalera™ comp. solution for injection, for intravenous, intramuscular and subcutaneous administration. Hevert ® Calmvalera™ comp. is a homeopathic drug indicated for the treatment of nervous disorders such as restlessness and sleep disorders, mild depressive states, and mental exhaustion. ( 1 dosage form intended by the applicant to be used with needle-based injection systems (e.g., cartridges). 7 Note that tests identified for these packages are not intended for dental anesthetic cartridge packages. 2.1.6 PLASTIC CONTAINERS FOR INTRAVENOUS INJECTIONS This type of package/delivery system refers to plastic containers fo

RHOGAM PLUS INJECTION SAFETY SHIELD SYRINGE 300MCG, 25Injection - Zienam Exporter from MumbaiRhoGAM Ultra-Filtered PLUS - FDA prescribing information

Botulinum toxin injections. These injections are used to treat the expression lines of the forehead and between the brows. They work by partially immobilizing the muscles that form expression lines so the skin smoothes out, although some deep expression lines may not go away. Botox is the familiar brand name An injection is needed every 8-13 weeks, depending on which injection is used. Some advantages. They are very effective. You do not have to remember to take pills. Once your body is used to the hormone, you often have no periods or very light periods. Particularly if you had heavy or painful periods, this is an advantage Vitamin K is necessary for synthesis of factors II (prothrombin), VII, IX, and X. Vitamin K is undetectable in cord blood. Lactobacillus (primary gut flora in breastfed babies) does not synthesize vitamin K. Breastmilk contains only small amounts of vitamin K (1 - 9 mcg/L); formula (53-66 mcg/L Rational use of medicines requires that patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and at the lowest cost to them and their community.A major global problemIrrational use of medicines is a major problem worldwide. WHO estimates that more than half of all medicines are prescribed. Polio (by injection, Salk) Accept immediately if feeling well and healthy. Rabies. Accept if prophylactic injection for occupation. Defer 12 months if bite sustained. Rh Immune Globulin (RhoGAM) Defer for 6 weeks after pregnancy, miscarriage or abortion. If in association with Rh incompatibly transfusion defer 12 months. Rocky Mountain Spotted.